Efficacy and safety of once weekly thyroxine versus daily thyroxine as maintenance therapy of hypothyroidism: a randomised controlled clinical trial
نویسندگان
چکیده
Official Journal of the Endocrine Society Sri Lanka. The Lanka Diabetes Endocrinology and Metabolism (SJDEM) publishes original research articles, reviews, other special features related to diabetes, endocrinology metabolism in humans human tissue.
منابع مشابه
Thyroxine-triiodothyronine combination therapy versus thyroxine monotherapy for clinical hypothyroidism: meta-analysis of randomized controlled trials.
CONTEXT In some patients symptoms of hypothyroidism persist despite therapy with T(4). OBJECTIVE The objective of the study was to compare the effectiveness of T(4)-T(3) combination vs. T(4) monotherapy for the treatment of clinical hypothyroidism in adults. DATA SOURCES PubMed, EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched in Septe...
متن کاملThyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism.
Standard therapy for patients with hypothyroidism is replacement with synthetic thyroxine (T4). However, thyroxine plus triiodothyronine (T3) replacement therapy resulted in marked improvements in several items of the Profile of Mood States and in a few indices of psychometric function and quality of life. The adequacy of thyroxine alone versus thyroxine plus triiodothyronine to treat hypothyro...
متن کاملSub-clinical Hypothyroidism: Complications and Effects of Thyroxine Therapy
Sub clinical hypothyroidism (SCH) is typically defined as elevated plasma TSH while free plasma T4 and T3 remain within normal range. SCH or mild thyroid failure is a common problem with a prevalence of 3% to 8% in the population. It increases with age and higher in women compared to men. There are various complications due to SCH such as, abnormal lipid metabolism, cardiac dysfunction, neurolo...
متن کاملdaily versus alternate day thyroxine therapy to maintain euthyroidism in children with congenital hypothyroidism
background: daily administration of thyroxine has proven efficacy in treatment of children with hypothyroidism. however, the possibility of treatment with longer dosing intervals that offers flexibility and choice in maintaining euthyroid state has not been tested in children. objectives: to study the efficacy of an alternate day regimen to maintain euthyroidism in children with congenital hypo...
متن کاملControlled clinical trial of combined triiodothyronine and thyroxine in the treatment of hypothyroidism.
A -double-blind crossover trial of a combined preparation of triiodothyronine and thyroxine (1:4 ratio) compared with thyroxine alone was conducted with 99 patients previously stabilized on. thyroxine as treatment for hypothyroidism. Four patients were excluded during the trial and eight afterwards owing to gross deficiencies in taking the tablets. Of the remaining 87 patients 42 (48%) had no -...
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ژورنال
عنوان ژورنال: Sri Lanka Journal of Diabetes Endocrinology and Metabolism
سال: 2022
ISSN: ['2012-998X']
DOI: https://doi.org/10.4038/sjdem.v13i2.7470